A Novel Crossover Dynamics of Variable‐Order Fractal‐Fractional Stochastic Diabetes Model: Numerical Simulations

Recent research has introduced piecewise fractional differential equations—particularly within deterministic‐stochastic frameworks—to better model complex and real‐world phenomena. However, their application to modeling the progression and treatment of diabetes remains limited. This paper proposes a novel mathematical framework for diabetes by incorporating piecewise stochastic‐deterministic differential equations that employ variable‐order fractional derivatives and fractal‐fractional operators. This integrated modeling approach allows for the simultaneous representation of memory effects, heterogeneous dynamics, and random fluctuations inherent in biological systems such as glucose–insulin interactions. To solve the proposed models, we develop two specialized numerical schemes: the nonstandard Grünwald–Letnikov finite difference method for the deterministic fractional component and a nonstandard Milstein method for handling the stochastic part. These techniques are specifically designed to preserve the qualitative behavior of the system, ensuring both stability and accuracy. Theoretical analysis establishes the stability properties of the proposed methods, while extensive numerical simulations—performed on a piecewise‐structured diabetes model—demonstrate their effectiveness. The results reveal significant insights into disease progression under varying physiological conditions and random perturbations. This comprehensive modeling framework thus provides a more realistic and personalized representation of diabetes dynamics, with potential applications in predicting treatment responses and optimizing individualized therapeutic strategies.

Authors

Institutions

Publication Details

Journal
Journal of Mathematics
Published
2025-01-01
DOI
https://doi.org/10.1155/jom/2986543
Citations
2
Primary Topic
Fractional Differential Equations Solutions
Type
article
Field-Weighted Citation Impact
2.74
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Novel Crossover Dynamics of Variable‐Order Fractal‐Fractional Stochastic Diabetes Model: Numerical Simulations

Ahlam M. Alghanmi, Zindoga Mukandavire, Hannah Al Ali, Muner M. Abou Hasan et al.
2 citations
Journal of Mathematics
Fractional Differential Equations Solutions
2.74
article

A Novel Crossover Dynamics of Variable‐Order Fractal‐Fractional Stochastic Diabetes Model: Numerical Simulations

Ahlam M. Alghanmi, Zindoga Mukandavire, Hannah Al Ali, Muner M. Abou Hasan, Seham M. Al‐Mekhlafi
article en
2 citations

Abstract

Recent research has introduced piecewise fractional differential equations—particularly within deterministic‐stochastic frameworks—to better model complex and real‐world phenomena. However, their application to modeling the progression and treatment of diabetes remains limited. This paper proposes a novel mathematical framework for diabetes by incorporating piecewise stochastic‐deterministic differential equations that employ variable‐order fractional derivatives and fractal‐fractional operators. This integrated modeling approach allows for the simultaneous representation of memory effects, heterogeneous dynamics, and random fluctuations inherent in biological systems such as glucose–insulin interactions. To solve the proposed models, we develop two specialized numerical schemes: the nonstandard Grünwald–Letnikov finite difference method for the deterministic fractional component and a nonstandard Milstein method for handling the stochastic part. These techniques are specifically designed to preserve the qualitative behavior of the system, ensuring both stability and accuracy. Theoretical analysis establishes the stability properties of the proposed methods, while extensive numerical simulations—performed on a piecewise‐structured diabetes model—demonstrate their effectiveness. The results reveal significant insights into disease progression under varying physiological conditions and random perturbations. This comprehensive modeling framework thus provides a more realistic and personalized representation of diabetes dynamics, with potential applications in predicting treatment responses and optimizing individualized therapeutic strategies.

Journal of MathematicsVol. 2025(1)
Sana'a University (YE), Future University in Egypt (EG), Taibah University (SA), Emirates Aviation University (AE), Yemenia University (YE)
Openalex Percentile: Top 10%
Fractional Differential Equations Solutions
2.74
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.