Evaluation of endocan biomarker levels in peri-implant crevicular fluid of healthy and diseased peri-implant sites: a cross-sectional study

Endocan demonstrates specificity as a biomarker for peri-implantitis, showing capacity to differentiate advanced peri-implant pathology from healthy tissues and peri-implant mucositis. These results suggest Endocan's potential utility for disease staging and monitoring in peri-implant care, providing a foundation for biomarker-based diagnostic approaches in implant dentistry.