Excess mortality in young cancer survivors compared with the general population in Italy: a retrospective study from the Italian population-based cohort of adolescents and young adult cancer survivors
The excess mortality is mostly due to the malignancy of the primary tumour, but an about 2-fold excess of mortality is also appreciable for non-cancer causes. Young adult cancer survivors face a sevenfold increase in all-cause mortality compared to the general population, with a notable rise in both cancer-related and non-cancer deaths. Thirty years post-diagnosis, the excess risk from cancer and non-cancer causes becomes nearly equal.
Authors
- Francesco Marinelli (ORCID: https://orcid.org/0000-0002-0047-456X)
- Massimo Vicentini (ORCID: https://orcid.org/0000-0002-0227-2523)
- Laura Botta (ORCID: https://orcid.org/0000-0002-2793-5338)
- Paolo Giorgi Rossi (ORCID: https://orcid.org/0000-0001-9703-2460)
- Annalisa Trama (ORCID: https://orcid.org/0000-0001-8220-9833)
- Lucìa Mangone (ORCID: https://orcid.org/0000-0002-5089-5178)
- Pamela Mancuso (ORCID: https://orcid.org/0000-0003-1609-2440)
- Isabella Bisceglia (ORCID: https://orcid.org/0000-0002-9225-781X)
- Alice Bernasconi
Institutions
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fonc.2025.1580953
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute