Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma
The experimental results demonstrate that PTK6 is a novel prognostic biomarker and potential therapeutic target for CM, highlighting its strong potential for real-world clinical applications.This study provides a theoretical basis for understanding PTK6's role in CM and its application in personalized treatment. However, further large-scale, multi-center studies are needed to verify its mechanistic role and clinical value.
Authors
- X. Liu (ORCID: https://orcid.org/0000-0002-6594-9677)
- Danli Tang
- Yan Lu (ORCID: https://orcid.org/0000-0003-1014-7842)
- Yanyan Niu (ORCID: https://orcid.org/0000-0001-7275-2787)
- Xiaodong Yao
- An Shi
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fonc.2025.1555302
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00