Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

The experimental results demonstrate that PTK6 is a novel prognostic biomarker and potential therapeutic target for CM, highlighting its strong potential for real-world clinical applications.This study provides a theoretical basis for understanding PTK6's role in CM and its application in personalized treatment. However, further large-scale, multi-center studies are needed to verify its mechanistic role and clinical value.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-07-30
DOI
https://doi.org/10.3389/fonc.2025.1555302
Primary Topic
Melanoma and MAPK Pathways
Type
article
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article

Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

X. Liu, Danli Tang, Yan Lu, Yanyan Niu et al.
1 links
Frontiers in Oncology
Melanoma and MAPK Pathways
article

Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

X. Liu, Danli Tang, Yan Lu, Yanyan Niu, Xiaodong Yao, An Shi
article en

Abstract

The experimental results demonstrate that PTK6 is a novel prognostic biomarker and potential therapeutic target for CM, highlighting its strong potential for real-world clinical applications.This study provides a theoretical basis for understanding PTK6's role in CM and its application in personalized treatment. However, further large-scale, multi-center studies are needed to verify its mechanistic role and clinical value.

Frontiers in OncologyVol. 15
Nantong University (CN), Affiliated Hospital of Nantong University (CN), Nanjing Medical University (CN)
No poverty
Openalex Percentile: Top 83%
Melanoma and MAPK Pathways
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