Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index

This study, which is based on CHARLS data, revealed that obesity-related indicators (WC, WHtR, BRI) significantly correlate with MCR risk. Metabolic disorders mediate the association of WHtR with MCR, confirming their central role in the link between obesity and cognition. Threshold effects were observed. The proposed method is to incorporate WHtR and CTI into community health assessments for early cognitive impairment screening, offering evidence for targeted interventions in resource-limited settings.