Impact of early β-blocker use on the incidence of sepsis and clinical outcomes following cardiac surgery: a retrospective cohort study

Early use of β-blocker after cardiac surgery was associated with a lower incidence of sepsis, with potential benefits observed in both short-term and long-term prognosis. These findings provide valuable evidence for optimizing perioperative drug management strategies.

Authors

Chengjian Guan (ORCID: https://orcid.org/0000-0002-8002-5499)
Bing Xiao (ORCID: https://orcid.org/0000-0002-8759-4600)
Shaotong Zhang (ORCID: https://orcid.org/0000-0002-2806-2989)
Qian Chen (ORCID: https://orcid.org/0000-0003-3697-5267)
Qianli Ma (ORCID: https://orcid.org/0000-0003-1564-3431)
Chen Yin

Institutions

Hebei Medical University (CN)
Second Hospital of Hebei Medical University (CN)

Publication Details

Journal: Frontiers in Pharmacology
Published: 2025-07-30
DOI: https://doi.org/10.3389/fphar.2025.1615868
Primary Topic: Cardiac, Anesthesia and Surgical Outcomes
Type: article
Field-Weighted Citation Impact: 0.00

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article

Impact of early β-blocker use on the incidence of sepsis and clinical outcomes following cardiac surgery: a retrospective cohort study

Chengjian Guan, Bing Xiao, Shaotong Zhang, Qian Chen et al.

Jul 30, 2025

Frontiers in Pharmacology

Cardiac, Anesthesia and Surgical Outcomes

article

Impact of early β-blocker use on the incidence of sepsis and clinical outcomes following cardiac surgery: a retrospective cohort study

Chengjian Guan, Bing Xiao, Shaotong Zhang, Qian Chen, Qianli Ma, Chen Yin

July 30, 2025article en

Abstract

Early use of β-blocker after cardiac surgery was associated with a lower incidence of sepsis, with potential benefits observed in both short-term and long-term prognosis. These findings provide valuable evidence for optimizing perioperative drug management strategies.

Frontiers in PharmacologyVol. 16

Hebei Medical University (CN), Second Hospital of Hebei Medical University (CN)

Good health and well-being

Openalex Percentile: Top 70%

Cardiac, Anesthesia and Surgical Outcomes

DOI Open Access PDF OpenAlex

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