Pulse rate variability is not the same as heart rate variability: findings from a large, diverse clinical population study
PPG-PRV is a poor surrogate for ECG- HRV as it significantly underestimated SDNN, rMSSD, and pNN50 across select chronic diseases. Given the widespread use of PPG-based devices and ubiquitous, incorrect assumption that PRV accurately reflects HRV, researchers, clinicians, and manufacturers must clearly distinguish between PRV and HRV in studies and product claims.
Authors
- Allen B. Kantrowitz
- Michael J. Wishon (ORCID: https://orcid.org/0000-0002-4509-0869)
- Samantha M. McDonald (ORCID: https://orcid.org/0000-0002-7191-5086)
- Harrison L. Wittels (ORCID: https://orcid.org/0000-0002-1244-3699)
- Kfir Ben‐David (ORCID: https://orcid.org/0000-0002-4321-2527)
- S. Howard Wittels
- Luis A. Feigenbaum (ORCID: https://orcid.org/0000-0003-1302-3239)
- Michael Morris
- Eric Renaghan
Institutions
- Unifor (NO)
- University of Miami (US)
- Florida International University (US)
- University of Florida (US)
- Research Organization for Information Science and Technology (JP)
- Mount Sinai Medical Center (US)
- Clinical Pharmacology of Miami (US)
- San Antonio Uniformed Services Health Education Consortium (US)
- Illinois State University (US)
- Joint Base San Antonio (US)
- Florida College (US)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fphys.2025.1630032
- Citations
- 4
- Primary Topic
- Non-Invasive Vital Sign Monitoring
- Type
- article
- Field-Weighted Citation Impact
- 2.70