IL-7 armed binary CAR T cell strategy to augment potency against solid tumors
The transgenic IL-7 armed binary CAR T cell approach could improve the efficacy of CAR-based therapies for solid tumors.
Authors
- Alejandro G. Torres Chavez (ORCID: https://orcid.org/0000-0002-7195-0965)
- Ann M. Leen (ORCID: https://orcid.org/0000-0002-4470-1760)
- Juan F. Vera (ORCID: https://orcid.org/0000-0002-8242-1233)
- Mary K. McKenna (ORCID: https://orcid.org/0000-0002-2357-1733)
- Pradip Bajgain (ORCID: https://orcid.org/0000-0002-4719-8451)
- Aman Gupta (ORCID: https://orcid.org/0000-0001-7028-457X)
- Neha Daga
Institutions
- Baylor College of Medicine (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1618404
- Citations
- 8
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 8.36
Funders
- Texas Children's Hospital
- National Institutes of Health
- National Cancer Institute