Case Report: Anaerococcus vaginalis spondylodiscitis diagnosed and cured based on nanopore targeted sequencing

Spondylodiscitis caused by <i>Anaerococcus vaginalis</i> has not been reported yet, making it worthy of further exploration. We closely monitored a patient who experienced worsened low back pain for 1 month and was unable to walk due to severe pain for 1 week. Through thorough examinations, the patient was diagnosed with lumbar disc herniation and a suspected case of spondylodiscitis, necessitating posterior lumbar surgery. All culture results returned negative. However, nanopore targeted sequencing (NTS) identified the presence of <i>Anaerococcus vaginalis</i>. Subsequent administration of appropriate antibiotics resulted in a favorable clinical outcome for the patient.