Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance
In conclusion, the B7/CD28 family plays an active role in the tumor immune microenvironment and cellular communication. B7H3 could serve as an indicator for predicting the outcome of HCC. Additional investigation is required to validate these discoveries in future groups of individuals and assess their viability as therapies guided by biomarkers.
Authors
- Sheng Wei (ORCID: https://orcid.org/0000-0001-6888-6301)
- Tao He (ORCID: https://orcid.org/0000-0002-7017-4503)
- Zimeng Wu (ORCID: https://orcid.org/0000-0002-7792-8291)
- Yan Cai (ORCID: https://orcid.org/0000-0002-7269-7375)
- Xianliang Tan
- Baoming Luo (ORCID: https://orcid.org/0000-0002-2331-5713)
- Yayun Xu (ORCID: https://orcid.org/0000-0002-8588-572X)
- Shuxian Chen
- Liying Xiao
- Xiaodi Liu
Institutions
- Sun Yat-sen University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Central People's Hospital of Zhanjiang (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1583597
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00