Antibiotic sensitivity pattern of environmental Vibrio cholerae of South Bengal

Vibrio cholerae isolates from crab, prawn, pond and river water samples in southern Bengal were isolated for assessing their antibiotic sensitivity pattern.Seven isolates were biochemically confirmed, with three positive for the ompW gene.Resistance to ceftriaxone and nalidixic acid was widespread, limiting their clinical utility.Ofloxacin and streptomycin were highly effective, showing complete sensitivity in several isolates.Concerningly, resistance to carbapenems like Meropenem, Imipenem and polymyxins was observed, posing challenges for managing severe infections.The study highlights the need for routine antimicrobial resistance (AMR) surveillance and emphasizes environmental sources as reservoirs of pathogenic, resistant V. cholerae.Future research should employ genomic approaches to better understand AMR mechanisms, informing public health strategies and therapeutic interventions in the region.