The Mediating Role of Blood Metabolites in the Association between Basal Metabolic Rate and Obstetrical Disorders: A Mendelian Randomization Analysis

Higher BMR may lower risks of hyperemesis gravidarum, ICP, poor fetal growth, and preterm delivery. Mannose mediates the protective effect of BMR on ICP, highlighting potential metabolic pathways for intervention.

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Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2025-07-24
DOI
https://doi.org/10.2174/0118715303400445250718112316
Primary Topic
Drug Transport and Resistance Mechanisms
Type
article
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0.00
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article

The Mediating Role of Blood Metabolites in the Association between Basal Metabolic Rate and Obstetrical Disorders: A Mendelian Randomization Analysis

Xiao Tan, Hongbo Qi, Yanqiong Gan, Qi Shi et al.
Endocrine Metabolic & Immune Disorders - Drug Targets
Drug Transport and Resistance Mechanisms
article

The Mediating Role of Blood Metabolites in the Association between Basal Metabolic Rate and Obstetrical Disorders: A Mendelian Randomization Analysis

Xiao Tan, Hongbo Qi, Yanqiong Gan, Qi Shi, Yu Tang
article en

Abstract

Higher BMR may lower risks of hyperemesis gravidarum, ICP, poor fetal growth, and preterm delivery. Mannose mediates the protective effect of BMR on ICP, highlighting potential metabolic pathways for intervention.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 25
North Sichuan Medical University (CN), Affiliated Hospital of North Sichuan Medical College (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 73%
Drug Transport and Resistance Mechanisms
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