Rheumatoid factor positivity in granulomatosis with polyangiitis: implications for clinical outcomes and immunological profiles

Rf positivity in GPA is associated with distinct clinical and immunological profiles, including an arthritis-dominant phenotype and reduced skin involvement. These findings suggest that Rf may influence disease course and organ involvement patterns, highlighting its potential as a biomarker for identifying distinct clinical phenotypes in GPA management.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-03-06
DOI
https://doi.org/10.55563/clinexprheumatol/n373g7
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Rheumatoid factor positivity in granulomatosis with polyangiitis: implications for clinical outcomes and immunological profiles

Ahmet Karataş, Süleyman Serdar Koca, Burak Öz, Gülşah Yamancan
Clinical and Experimental Rheumatology
Vasculitis and related conditions
article

Rheumatoid factor positivity in granulomatosis with polyangiitis: implications for clinical outcomes and immunological profiles

Ahmet Karataş, Süleyman Serdar Koca, Burak Öz, Gülşah Yamancan
article en

Abstract

Rf positivity in GPA is associated with distinct clinical and immunological profiles, including an arthritis-dominant phenotype and reduced skin involvement. These findings suggest that Rf may influence disease course and organ involvement patterns, highlighting its potential as a biomarker for identifying distinct clinical phenotypes in GPA management.

Clinical and Experimental Rheumatology
Fırat University (TR)
Zero hunger
Openalex Percentile: Top 71%
Vasculitis and related conditions
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