CATALYST FREE SYNTHESIS OF NOVEL 6-CHLORO-3- ISOPROPYL-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES AS PHARMA INTERMEDIATE

We synthesised novel compounds containing 6-chloro-3-isopropyl-1-methylpyrimidine-2,4(1H,3H)-dione without a catalyst. These molecules can potentially demonstrate exceptional anticancer, antiviral, and bactericidal properties while being safe for use. These compounds represent a minor modification of Mavacamten. Additionally, we can efficiently produce them on an industrial scale. They may also serve as active components in medicinal and veterinary antifungal agents.

Authors

Publication Details

Journal
RASAYAN Journal of Chemistry
Published
2025-01-01
DOI
https://doi.org/10.31788/rjc.2025.1839314
Citations
1
Primary Topic
Synthesis and Characterization of Heterocyclic Compounds
Type
article
Field-Weighted Citation Impact
0.94
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article

CATALYST FREE SYNTHESIS OF NOVEL 6-CHLORO-3- ISOPROPYL-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES AS PHARMA INTERMEDIATE

Sunil Kumar Nechipadappu, Rahul D. Shingare, Sudhakar Bansod, B.V. Subba Reddy
1 citations
RASAYAN Journal of Chemistry
Synthesis and Characterization of Heterocyclic Compounds
0.94
article

CATALYST FREE SYNTHESIS OF NOVEL 6-CHLORO-3- ISOPROPYL-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES AS PHARMA INTERMEDIATE

Sunil Kumar Nechipadappu, Rahul D. Shingare, Sudhakar Bansod, B.V. Subba Reddy
article en
1 citations

Abstract

We synthesised novel compounds containing 6-chloro-3-isopropyl-1-methylpyrimidine-2,4(1H,3H)-dione without a catalyst. These molecules can potentially demonstrate exceptional anticancer, antiviral, and bactericidal properties while being safe for use. These compounds represent a minor modification of Mavacamten. Additionally, we can efficiently produce them on an industrial scale. They may also serve as active components in medicinal and veterinary antifungal agents.

RASAYAN Journal of ChemistryVol. 18(03)
Openalex Percentile: Top 23%
Synthesis and Characterization of Heterocyclic Compounds
0.94
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CATALYST FREE SYNTHESIS OF NOVEL 6-CHLORO-3- ISOPROPYL-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES AS PHARMA INTERMEDIATE — Sunil Kumar Nechipadappu, Rahul D. Shingare, et al. · RASAYAN Journal of Chemistry (2025) | TGRS Research Map | TGRS