CATALYST FREE SYNTHESIS OF NOVEL 6-CHLORO-3- ISOPROPYL-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES AS PHARMA INTERMEDIATE
We synthesised novel compounds containing 6-chloro-3-isopropyl-1-methylpyrimidine-2,4(1H,3H)-dione without a catalyst. These molecules can potentially demonstrate exceptional anticancer, antiviral, and bactericidal properties while being safe for use. These compounds represent a minor modification of Mavacamten. Additionally, we can efficiently produce them on an industrial scale. They may also serve as active components in medicinal and veterinary antifungal agents.
Authors
- Sunil Kumar Nechipadappu (ORCID: https://orcid.org/0000-0002-0042-743X)
- Rahul D. Shingare (ORCID: https://orcid.org/0000-0002-8690-2229)
- Sudhakar Bansod (ORCID: https://orcid.org/0000-0003-2118-7647)
- B.V. Subba Reddy
Publication Details
- Journal
- RASAYAN Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.31788/rjc.2025.1839314
- Citations
- 1
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.94