Efficient photocatalytic synthesis of benzylhydrazine

In this paper, an efficient synthesis of benzylhydrazine derivatives from unactivated phenylethanol analogues was successfully developed under mild redox-neutral reaction conditions. At the same time, it was also proved that a wide range of phenylethanol analogues and azodicarboxylates can be successfully applied in this fragment coupling transformation. Moreover, this method can be applied to the synthesis of active molecules of isocarboxazid.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2025-01-01
DOI
https://doi.org/10.1039/d5ob00771b
Primary Topic
Radical Photochemical Reactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficient photocatalytic synthesis of benzylhydrazine

Bingzhen Ma, Fanrong Zeng, Yangyang Li, Yuhui Zhang et al.
Organic & Biomolecular Chemistry
Radical Photochemical Reactions
article

Efficient photocatalytic synthesis of benzylhydrazine

Bingzhen Ma, Fanrong Zeng, Yangyang Li, Yuhui Zhang, Meiqi Zhou, Jiafan Wang
article en

Abstract

In this paper, an efficient synthesis of benzylhydrazine derivatives from unactivated phenylethanol analogues was successfully developed under mild redox-neutral reaction conditions. At the same time, it was also proved that a wide range of phenylethanol analogues and azodicarboxylates can be successfully applied in this fragment coupling transformation. Moreover, this method can be applied to the synthesis of active molecules of isocarboxazid.

Organic & Biomolecular ChemistryVol. 23(32)
State Ethnic Affairs Commission (CN), North Minzu University (CN)
Natural Science Foundation of Ningxia Province, Fundamental Research Funds for the Central Universities
Openalex Percentile: Top 86%
Radical Photochemical Reactions
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