Histone Lactylation Promotes Proliferation and Migration of TNBC Cells via Upregulating MCM7 Transcription
Highlight:1.In triple-negative breast cancer (TNBC) cells, histone lactylation significantly increases, which is closely related to their proliferation and migration.2. The mechanism by which histone lactylation influences the survival and growth of TNBC cells involves the regulation of MCM7 transcription.
Authors
- Chaoxian Wang
- Sili Jin
- Guangfa Xia
- Fei Xiao (ORCID: https://orcid.org/0000-0003-3370-4234)
- Ziran Zhang (ORCID: https://orcid.org/0000-0002-7835-8788)
- Xingxia Yang
Institutions
- Jiaxing University (CN)
- Ningbo University Affiliated Hospital (CN)
Publication Details
- Journal
- The Tohoku Journal of Experimental Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1620/tjem.2025.j096
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Bureau of Jiaxing City