Unilateral optic neuritis associated with MOG antibodies in a pediatric patient

Case report of a 14-year-old male presented with acute painless vision loss and left optic disc swelling. Extensive diagnostic investigations, including magnetic resonance imaging and serum MOG antibody testing, were conducted. Magnetic resonance imaging showed an extensive T2 hyperintense signal in the anterior portion of the left optic nerve without involving chiasm or retrochiasmatic areas. The management strategy involved intravenous methylprednisolone followed by azathioprine, resulting in complete vision recovery. This case highlights the importance of considering MOG antibody-associated optic [...]

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Publication Details

Journal
Revista Brasileira de Oftalmologia
Published
2025-01-01
DOI
https://doi.org/10.37039/1982.8551.20250049
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
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article

Unilateral optic neuritis associated with MOG antibodies in a pediatric patient

Matheus Luiz de Souza Céfalo, Fabiano Reis, Danilo de Assis Pereira, Valéria Cristina Santucci Ramos et al.
Revista Brasileira de Oftalmologia
Peripheral Neuropathies and Disorders
article

Unilateral optic neuritis associated with MOG antibodies in a pediatric patient

Matheus Luiz de Souza Céfalo, Fabiano Reis, Danilo de Assis Pereira, Valéria Cristina Santucci Ramos, Marcela Izabelle Fernandes dos Reis, Bernardo Savaya Lima, Daniel Akerman Zimerman
article en

Abstract

Case report of a 14-year-old male presented with acute painless vision loss and left optic disc swelling. Extensive diagnostic investigations, including magnetic resonance imaging and serum MOG antibody testing, were conducted. Magnetic resonance imaging showed an extensive T2 hyperintense signal in the anterior portion of the left optic nerve without involving chiasm or retrochiasmatic areas. The management strategy involved intravenous methylprednisolone followed by azathioprine, resulting in complete vision recovery. This case highlights the importance of considering MOG antibody-associated optic [...]

Revista Brasileira de OftalmologiaVol. 84
Good health and well-being
Openalex Percentile: Top 72%
Peripheral Neuropathies and Disorders
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Unilateral optic neuritis associated with MOG antibodies in a pediatric patient — Matheus Luiz de Souza Céfalo, Fabiano Reis, et al. · Revista Brasileira de Oftalmologia (2025) | TGRS Research Map | TGRS