Oxamate suppresses whole-body energy metabolism at rest and during exercise in mice by inhibiting fat oxidation and altering lactate dynamics
Oxamate suppressed whole-body energy metabolism by inhibiting fat oxidation and altering lactate dynamics in vivo. These results provide novel insights into the systemic metabolic effects of oxamate and highlight the need for further investigation of its impact under different physiological conditions.
Authors
- Inkwon Jang (ORCID: https://orcid.org/0000-0003-4736-8550)
- Taeho Kim
- Hun‐Young Park (ORCID: https://orcid.org/0000-0002-9901-7624)
- Jae-Moo So
- Deunsol Hwang (ORCID: https://orcid.org/0000-0002-9323-7183)
- Jiseon Han (ORCID: https://orcid.org/0009-0003-3496-4748)
- Sunghwan Kyun
- Kiwon Lim (ORCID: https://orcid.org/0000-0003-3222-1783)
- Sung-Woo Kim (ORCID: https://orcid.org/0000-0001-5976-277X)
- Jisu Kim (ORCID: https://orcid.org/0000-0003-2344-6235)
- Chi-Ho Lee
- Jong-Hoon Park
Institutions
- Korea University (KR)
- Konkuk University (KR)
Publication Details
- Journal
- Physical Activity and Nutrition
- Published
- 2025-06-30
- DOI
- https://doi.org/10.20463/pan.2025.0011
- Citations
- 1
- Primary Topic
- Muscle metabolism and nutrition
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Research Foundation
- Konkuk University
- Ministry of Education
- National Research Foundation of Korea