An asymmetric biomimetic aldol reaction of glycinate with aliphatic aldehydes for efficient synthesis of chiral β-hydroxy-α-amino acid esters

A direct asymmetric aldol reaction of glycinate with aliphatic aldehydes was developed in the presence of a chiral pyridoxal catalyst.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00653h
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
0.00

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article

An asymmetric biomimetic aldol reaction of glycinate with aliphatic aldehydes for efficient synthesis of chiral β-hydroxy-α-amino acid esters

Siqi Liu, Ting Ma, Baoguo Zhao, Dong Ma et al.
Organic Chemistry Frontiers
Asymmetric Synthesis and Catalysis
article

An asymmetric biomimetic aldol reaction of glycinate with aliphatic aldehydes for efficient synthesis of chiral β-hydroxy-α-amino acid esters

Siqi Liu, Ting Ma, Baoguo Zhao, Dong Ma, Tao Liu, Mingming Lu, Guoqing Zhao
article en

Abstract

A direct asymmetric aldol reaction of glycinate with aliphatic aldehydes was developed in the presence of a chiral pyridoxal catalyst.

Organic Chemistry FrontiersVol. 12(22)
Shanghai Normal University (CN)
National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, National Key Research and Development Program of China
Openalex Percentile: Top 86%
Asymmetric Synthesis and Catalysis
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