Augmentation of the Anterior Mitral Leaflet With an Untreated Autologous Pericardial Patch in Functional Mitral Regurgitation
Background: Patch augmentation of the anterior mitral leaflet (AAML) is being used to treat functional mitral regurgitation (fMR) with the choice of patch material, however, still being a matter of debate. Therefore, the aim of this study was to determine the early‐ and 1‐year results of AAML for fMR. Methods: Between 2020 and 2022, 30 patients underwent AAML for Carpentier Type IIIb fMR using an untreated autologous pericardial patch in our institution. The mean age of the patients was 61.3 ± 19.3 years, and 16 patients (53.3%) were male. Early‐ and 1‐year results of mitral valve repair were assessed via clinical follow‐up including echocardiographic examination. Results: Twenty patients (66.7%) were operated on through a right mini‐thoracotomy and 10 patients (33.3%) via a median sternotomy, with 19 patients (63.3%) receiving a concomitant procedure. Three patients (10%) required postoperative mechanical circulatory support (MCS), with one of those patients (3.3%) deceasing due to multiple organ failure. Postoperative echocardiography showed that all patients (100%) had either no or mild MR. Freedom from moderate to severe MR was 100% ( n = 29) at discharge as well as after a 1.1 ± 0.17‐year follow‐up ( n = 26; with an additional three patients (10%) that deceased during the first postoperative year due to non–valve‐related causes). No patient required mitral valve‐related reoperation or intervention. Conclusions: AAML using an untreated autologous pericardial patch is a safe and reproducible surgical technique for fMR, with promising early results up to a 1‐year follow‐up. Further follow‐up is warranted to determine long‐term results especially with regard to the durability of mitral valve repair.
Authors
- Hug Aubin (ORCID: https://orcid.org/0000-0001-9289-8927)
- Egzon Memedi
- I. Tudorache (ORCID: https://orcid.org/0000-0003-2367-3606)
- Philipp Rellecke
- Artur Lichtenberg (ORCID: https://orcid.org/0000-0001-8580-6369)
- Dmytro Stadnik (ORCID: https://orcid.org/0000-0002-5109-222X)
- B. Ramadani
- Tong Li (ORCID: https://orcid.org/0000-0002-2608-2855)
- Stephan Urs Sixt (ORCID: https://orcid.org/0000-0003-4416-2266)
Institutions
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Journal of Cardiac Surgery
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/jocs/3901792
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00