Augmentation of the Anterior Mitral Leaflet With an Untreated Autologous Pericardial Patch in Functional Mitral Regurgitation

Background: Patch augmentation of the anterior mitral leaflet (AAML) is being used to treat functional mitral regurgitation (fMR) with the choice of patch material, however, still being a matter of debate. Therefore, the aim of this study was to determine the early‐ and 1‐year results of AAML for fMR. Methods: Between 2020 and 2022, 30 patients underwent AAML for Carpentier Type IIIb fMR using an untreated autologous pericardial patch in our institution. The mean age of the patients was 61.3 ± 19.3 years, and 16 patients (53.3%) were male. Early‐ and 1‐year results of mitral valve repair were assessed via clinical follow‐up including echocardiographic examination. Results: Twenty patients (66.7%) were operated on through a right mini‐thoracotomy and 10 patients (33.3%) via a median sternotomy, with 19 patients (63.3%) receiving a concomitant procedure. Three patients (10%) required postoperative mechanical circulatory support (MCS), with one of those patients (3.3%) deceasing due to multiple organ failure. Postoperative echocardiography showed that all patients (100%) had either no or mild MR. Freedom from moderate to severe MR was 100% ( n = 29) at discharge as well as after a 1.1 ± 0.17‐year follow‐up ( n = 26; with an additional three patients (10%) that deceased during the first postoperative year due to non–valve‐related causes). No patient required mitral valve‐related reoperation or intervention. Conclusions: AAML using an untreated autologous pericardial patch is a safe and reproducible surgical technique for fMR, with promising early results up to a 1‐year follow‐up. Further follow‐up is warranted to determine long‐term results especially with regard to the durability of mitral valve repair.

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Journal
Journal of Cardiac Surgery
Published
2025-01-01
DOI
https://doi.org/10.1155/jocs/3901792
Primary Topic
Cardiac Valve Diseases and Treatments
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article
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article

Augmentation of the Anterior Mitral Leaflet With an Untreated Autologous Pericardial Patch in Functional Mitral Regurgitation

Hug Aubin, Egzon Memedi, I. Tudorache, Philipp Rellecke et al.
Journal of Cardiac Surgery
Cardiac Valve Diseases and Treatments
article

Augmentation of the Anterior Mitral Leaflet With an Untreated Autologous Pericardial Patch in Functional Mitral Regurgitation

Hug Aubin, Egzon Memedi, I. Tudorache, Philipp Rellecke, Artur Lichtenberg, Dmytro Stadnik, B. Ramadani, Tong Li, Stephan Urs Sixt
article en

Abstract

Background: Patch augmentation of the anterior mitral leaflet (AAML) is being used to treat functional mitral regurgitation (fMR) with the choice of patch material, however, still being a matter of debate. Therefore, the aim of this study was to determine the early‐ and 1‐year results of AAML for fMR. Methods: Between 2020 and 2022, 30 patients underwent AAML for Carpentier Type IIIb fMR using an untreated autologous pericardial patch in our institution. The mean age of the patients was 61.3 ± 19.3 years, and 16 patients (53.3%) were male. Early‐ and 1‐year results of mitral valve repair were assessed via clinical follow‐up including echocardiographic examination. Results: Twenty patients (66.7%) were operated on through a right mini‐thoracotomy and 10 patients (33.3%) via a median sternotomy, with 19 patients (63.3%) receiving a concomitant procedure. Three patients (10%) required postoperative mechanical circulatory support (MCS), with one of those patients (3.3%) deceasing due to multiple organ failure. Postoperative echocardiography showed that all patients (100%) had either no or mild MR. Freedom from moderate to severe MR was 100% ( n = 29) at discharge as well as after a 1.1 ± 0.17‐year follow‐up ( n = 26; with an additional three patients (10%) that deceased during the first postoperative year due to non–valve‐related causes). No patient required mitral valve‐related reoperation or intervention. Conclusions: AAML using an untreated autologous pericardial patch is a safe and reproducible surgical technique for fMR, with promising early results up to a 1‐year follow‐up. Further follow‐up is warranted to determine long‐term results especially with regard to the durability of mitral valve repair.

Journal of Cardiac SurgeryVol. 2025(1)
Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 70%
Cardiac Valve Diseases and Treatments
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