A lysosomal fluorescent probe for the imaging of viscosity in tumoral ferroptosis and rheumatoid arthritis mice models
Viscosity, as an important micro-environment parameter, is closely related to the occurrence and progression of various diseases. Herein, we have developed a novel fluorescent probe (BIB) for lysosomal viscosity detection. Interestingly, using BIB, <i>in vivo</i> imaging of viscosity fluctuations in tumoral ferroptosis and rheumatoid arthritis models has been successfully achieved.
Authors
- Xihua Yang (ORCID: https://orcid.org/0000-0002-5990-2186)
- Li Fan (ORCID: https://orcid.org/0000-0002-4218-6638)
- Qi Zan
- Chuan Dong (ORCID: https://orcid.org/0000-0002-6291-8357)
- Shaomin Shuang (ORCID: https://orcid.org/0000-0003-2880-5444)
- Hui Wang (ORCID: https://orcid.org/0000-0002-5253-1204)
- Bo Lin (ORCID: https://orcid.org/0009-0002-5815-4662)
- Yongming Yang (ORCID: https://orcid.org/0000-0002-8816-2500)
- Rui Wang (ORCID: https://orcid.org/0009-0001-9020-4984)
Institutions
- Shanxi Medical University (CN)
- Shanxi University (CN)
- Mianyang Central Hospital (CN)
- Shanxi Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03040d
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China