Decarboxylative chlorination of α,β-unsaturated acids
Herein, an unprecedented oxidative decarboxylative chlorination of α,β-unsaturated acids for α-chloroketones is reported. This green and sustainable approach employs Fe(III)-catalyzed LMCT to generate a chloride radical from non-hazardous LiCl under violet light irradiation. Molecular oxygen serves as the oxygen source for the ketone group, while naturally abundant unsaturated acids replace unstable alkenes or alkynes, enabling efficient and eco-friendly synthesis of α-phenacyl chlorides.
Authors
- Souvik Maiti (ORCID: https://orcid.org/0000-0001-9897-1419)
- Subal Mondal
- Soumya K. Ghosh (ORCID: https://orcid.org/0000-0001-8359-581X)
- Pradyut Ghosh (ORCID: https://orcid.org/0000-0002-5503-6428)
- Siba P. Midya (ORCID: https://orcid.org/0000-0002-4397-0811)
- Soumya Mondal (ORCID: https://orcid.org/0009-0003-0709-0803)
- Tarun Jana
Institutions
- Indian Association for the Cultivation of Science (IN)
- Ramakrishna Mission Vidyamandira (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03038b
- Citations
- 1
- Primary Topic
- Vanadium and Halogenation Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Science and Engineering Research Board