The Visual Acuity Course in Stargardt Disease

Visual acuity decline in Stargardt disease type 1 follows a nonlinear course, varying by age of onset. We found that a large sample size is required for visual acuity-based trials, which makes visual acuity an impractical primary end point. However, the generated models in this study will help clinicians in counseling their patients.

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Publication Details

Journal
American Journal of Ophthalmology
Published
2025-07-24
DOI
https://doi.org/10.1016/j.ajo.2025.07.024
Citations
1
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.81

Funders

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article

The Visual Acuity Course in Stargardt Disease

Catherina H. Z. Li, Dyon Valkenburg, Rob W.J. Collin, Patty P.A. Dhooge et al.
1 citations
American Journal of Ophthalmology
Retinal Development and Disorders
0.81
article

The Visual Acuity Course in Stargardt Disease

Catherina H. Z. Li, Dyon Valkenburg, Rob W.J. Collin, Patty P.A. Dhooge, Jeroen Pas, Joanna IntHout, M M Groenewoud Johannes, B Hoyng Carel
article en
1 citations

Abstract

Visual acuity decline in Stargardt disease type 1 follows a nonlinear course, varying by age of onset. We found that a large sample size is required for visual acuity-based trials, which makes visual acuity an impractical primary end point. However, the generated models in this study will help clinicians in counseling their patients.

American Journal of OphthalmologyVol. 279
Radboud University Nijmegen (NL), Radboud University Medical Center (NL)
Foundation Fighting Blindness
Good health and well-being
Openalex Percentile: Top 25%
Retinal Development and Disorders
0.81
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