Guidelines for the prevention and treatment of iodine contrast agent-related acute kidney injury (ICR-AKI) in endovascular treatment of lower extremity arteries

Lower extremity arterial disease is extremely complex. Endovascular treatment for lower extremity arteries is minimally invasive, and patients may recover soon after operation. Intervention for lower extremity arterial disease requires a high dose of iodinated contrast agents, and the incidence of iodinated contrast agent-related acute kidney injury (AKI) after intervention is not low, and is independently related to in-hospital mortality. To prevent and treat iodinated contrast agent-related AKI, and to benefit patients more, this guideline is established based on existing guidelines, expert opinions, new evidence, and clinical practice. The consensus includes definition, pathological characteristics, risk factors, risk assessment, hydration protocol, and medications of iodinated contrast agent-related AKI.