NHC/photoredox dual catalysis directs <i>N</i> -methyl radical coupling for decarboxylative synthesis of α- <i>N</i> -aryl amino ketones
Synergistic NHC/photoredox catalysis enables α- N -aryl amino ketone synthesis via stabilized N -methyl radicals, preventing dimerization. Base-mediated radical generation and acyl azolium-guided coupling ensure broad scope under mild conditions.
Authors
- Shilin Zhou (ORCID: https://orcid.org/0000-0002-6052-9278)
- Wenying Zhao (ORCID: https://orcid.org/0000-0001-5795-935X)
- Weikun Zeng
- Yi Jin (ORCID: https://orcid.org/0000-0003-0149-2150)
- Jun Zhou (ORCID: https://orcid.org/0009-0001-4801-9873)
Institutions
- Yunnan University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00923e
- Citations
- 2
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China