Gabapentin-induced sub-chronic neurotoxicity in rats and the protective role of alpha-tocopherol
GBP in high doses had neurotoxic effects, disrupted hippocampal tissues, and increased the number of degenerated cells. Alpha-tocopherol treatment significantly attenuated the deleterious effects induced by GBP.
Authors
- Maha Emad Eldein
- Mohammad El-Kattan (ORCID: https://orcid.org/0000-0002-8957-4531)
- Walaa Awad
- Fatma Abdel Maksoud (ORCID: https://orcid.org/0000-0003-1436-3219)
- Ahmed Elshatory (ORCID: https://orcid.org/0000-0001-8825-2277)
- Mahmoud M. Khattab (ORCID: https://orcid.org/0000-0002-3217-5417)
- Eman Saeed
- Nada Elsayed Abdel-Roaf
Institutions
- Cairo University (EG)
- Mansoura University (EG)
- Ministry of Health (KW)
Publication Details
- Journal
- Turkish Journal of Pathology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5146/tjpath.2025.14236
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91