QD–Aptamer Biocomplexes with Specificity to the Epidermal Growth Factor Receptor

Complexes based on quantum dots (QDs) and aptamers can combine the luminescence properties of nanoparticles and the specificity of interaction of an aptamer with a target. In this work, a method for obtaining the complexes of QDs of various types (CdSe/ZnS and InP/ZnS) with DNA aptamers Gol1 and U8 was proposed. These aptamers determine the specificity of interaction with the epidermal growth factor receptor (EGFR). The complexes obtained have great potential in the field of optical visualization and diagnostics of oncological diseases.