A Rare Case of <i>Cyberlindnera jadinii</i> Fungemia in a Kidney Transplant Recipient: A Case Report

Despite revolutionary improvements in mortality, cardiovascular events, and quality of life, kidney transplantation has been plagued with perioperative mortality, graft rejection, and immunosuppression-associated complications, most commonly infections. Fungal infections in particular only account for 5% of all cases but have the worst outcomes, with mortality ranging between 25% and 80% in solid organ transplant recipients. <i>Candida</i>, <i>Cryptococcus</i>, and <i>Aspergillus</i> species are the commonest causative agents, and isolated cases of other species have been reported in other immunosuppressed pathologies. Here, we present the first recorded case of <i>Cyberlindnera jadinii</i> fungemia in a kidney transplant recipient, highlighting the need for close surveillance, early diagnosis, and potentially continuing posttransplant antifungal prophylaxis beyond the current recommended duration.

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Publication Details

Journal
Case Reports in Transplantation
Published
2025-01-01
DOI
https://doi.org/10.1155/crit/3478928
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
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article

A Rare Case of Cyberlindnera jadinii Fungemia in a Kidney Transplant Recipient: A Case Report

David C. Mulligan, Jayaditya Devpal Patil, Hiroshi Sogawa
2 links
Case Reports in Transplantation
Antifungal resistance and susceptibility
article

A Rare Case of Cyberlindnera jadinii Fungemia in a Kidney Transplant Recipient: A Case Report

David C. Mulligan, Jayaditya Devpal Patil, Hiroshi Sogawa
article en

Abstract

Despite revolutionary improvements in mortality, cardiovascular events, and quality of life, kidney transplantation has been plagued with perioperative mortality, graft rejection, and immunosuppression-associated complications, most commonly infections. Fungal infections in particular only account for 5% of all cases but have the worst outcomes, with mortality ranging between 25% and 80% in solid organ transplant recipients. <i>Candida</i>, <i>Cryptococcus</i>, and <i>Aspergillus</i> species are the commonest causative agents, and isolated cases of other species have been reported in other immunosuppressed pathologies. Here, we present the first recorded case of <i>Cyberlindnera jadinii</i> fungemia in a kidney transplant recipient, highlighting the need for close surveillance, early diagnosis, and potentially continuing posttransplant antifungal prophylaxis beyond the current recommended duration.

Case Reports in TransplantationVol. 2025(1)
Yale New Haven Hospital (US)
Openalex Percentile: Top 77%
Antifungal resistance and susceptibility
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