"Diagnosis of Immunodeficiency Disease in Pediatric Patients with Recurrent Respiratory Infection"

Respiratory pathology represents a great challenge for health institutions, due to its frequency, its diagnostic and therapeutic complexity and the burden it represents in economic and vital costs.For the most part, these infections only affect the upper respiratory tract and can be considered mild in immunocompetent individuals, with a benign and self-limiting course.It is difficult to establish the limit between normal and pathological in terms of the number of infections presented by a child in a given time.The bodys defense against infections is carried out by the immune system.Due to its possibility of presentation between one and five years and its association with pulmonary pathology, we must focus our attention on: immunodeficiency related to malnutrition, immunodeficiency due to infections, immunodeficiency due to the use of drugs, prematurity and inborn errors of immunity, such as antibodies defects.Therefore, whenever the diagnostic possibility of the child who presents with recurrent respiratory infections disease, whether primary (inborn errors of immunity) or secondary, we propose and algorithm, with which we have more than 15 years of experience in our Pediatric Immunology Services, where children with recurrent respiratory infections are treated.