Role of a new truncated CD74 isoform in increased IL-17 secretion from stromal-immune cell interactions
This study identified truncated CD74 isoform as a novel molecule directly involved in high IL-17 secretion resulting from cell interactions. Inhibition of this truncated CD74 could represent a new therapeutic option for diseases with IL-17 involvement.
Authors
- Marlène Bailly
- Pierre Miossec (ORCID: https://orcid.org/0000-0002-3280-6346)
- Jean‐Jacques Pin
- Mélissa Noack
- Laura Durix
Institutions
- Hospices Civils de Lyon (FR)
- Hôpital Edouard Herriot (FR)
Publication Details
- Journal
- Clinical & Experimental Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/cei/uxaf047
- Citations
- 1
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.80