CDDO-Me triggers ROS-dependent ferroptosis and apoptosis in cervical cancer via targeting PI3K/Nrf2 pathway

CDDO-Me induces CC cell lines apoptosis and ferroptosis through the PI3K/Nrf2 signaling pathway, for exerting anti-proliferation effects.

Authors

W. Li
Anna Han
Xinyue Feng
Mengying Wang (ORCID: https://orcid.org/0000-0001-7591-522X)
Pan Du
Liyan Chen

Institutions

Yanbian University (CN)
State Ethnic Affairs Commission (CN)
Yanbian University Hospital (CN)

Publication Details

Journal: Food and Chemical Toxicology
Published: 2025-07-24
DOI: https://doi.org/10.1016/j.fct.2025.115664
Primary Topic: Ferroptosis and cancer prognosis
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
Department of Science and Technology of Jilin Province

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article

CDDO-Me triggers ROS-dependent ferroptosis and apoptosis in cervical cancer via targeting PI3K/Nrf2 pathway

W. Li, Anna Han, Xinyue Feng, Mengying Wang et al.

Jul 24, 2025

Food and Chemical Toxicology

Ferroptosis and cancer prognosis

article

CDDO-Me triggers ROS-dependent ferroptosis and apoptosis in cervical cancer via targeting PI3K/Nrf2 pathway

W. Li, Anna Han, Xinyue Feng, Mengying Wang, Pan Du, Liyan Chen

July 24, 2025article en

Abstract

CDDO-Me induces CC cell lines apoptosis and ferroptosis through the PI3K/Nrf2 signaling pathway, for exerting anti-proliferation effects.

Food and Chemical ToxicologyVol. 204

Yanbian University (CN), State Ethnic Affairs Commission (CN), Yanbian University Hospital (CN)

National Natural Science Foundation of China, Department of Science and Technology of Jilin Province

Good health and well-being

Openalex Percentile: Top 71%

Ferroptosis and cancer prognosis

DOI Open Access PDF OpenAlex

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CDDO-Me triggers ROS-dependent ferroptosis and apoptosis in cervical cancer via targeting PI3K/Nrf2 pathway — W. Li, Anna Han, et al. · Food and Chemical Toxicology (2025) | TGRS Research Map | TGRS