Aberrant placental structure is corrected with repeated nanoparticle-mediated IGF1 treatments in a Guinea pig model of fetal growth restriction
This data demonstrates repeated nanoparticle-mediated <i>hIGF1</i> delivery corrects aberrant placenta structure during FGR and placental insufficiency likely leading to improved gas exchange and transfer of nutrients to the fetus restoring fetal growth.
Authors
- Helen Jones (ORCID: https://orcid.org/0000-0001-7356-8420)
- Jaimi A. Gray (ORCID: https://orcid.org/0000-0002-4758-8572)
- Baylea N. Davenport (ORCID: https://orcid.org/0000-0001-5804-2340)
- Rebecca L. Wilson (ORCID: https://orcid.org/0000-0002-3867-7784)
- Alyssa Williams (ORCID: https://orcid.org/0000-0003-1690-0110)
- Edward Stanley
Institutions
- Planetary Science Institute (US)
- Florida Museum of Natural History (US)
- University of Florida (US)
- The University of Texas at Austin (US)
Publication Details
- Journal
- Translational Research in Anatomy
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1016/j.tria.2025.100424
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for the National Institutes of Health
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development