Gamma-tocopherol vitamin E enhances the cytotoxicity of p-cresyl sulfate to renal tubular cells
In this study, our results constitute the first demonstration that γ-tocopherol may cause renal-cell damage and enhance PCS-induced toxicity to renal cells via the apoptotic cell-death pathway.
Authors
- Yi‐Chung Chien
- Yung‐Luen Yu (ORCID: https://orcid.org/0000-0002-9745-1726)
- Chyou-Wei Wei
- Shu-Cing Wu
- Giou‐Teng Yiang (ORCID: https://orcid.org/0000-0001-8473-3591)
- Yilin Chen (ORCID: https://orcid.org/0009-0000-9552-5990)
- Lin Jian
- Jiayan Wu (ORCID: https://orcid.org/0000-0001-6048-405X)
- Ying‐Ru Pan
Institutions
- Asia University (TW)
- Tzu Chi College of Technology (TW)
- China Medical University (TW)
- Tzu Chi University (TW)
- China Medical University Hospital (TW)
- Changhua Christian Hospital (TW)
- National Ilan University (TW)
- Hungkuang University (TW)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s40001-025-02942-4
- Citations
- 2
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- China Medical University Hospital
- Ministry of Science and Technology, Taiwan
- National Health Research Institutes
- China Medical University
- Taipei Tzu Chi Hospital
- China Medical University, Taiwan
- National Science and Technology Council
- Division of Materials Research