Progression of liver fibrosis after metabolic bariatric surgery in a MASLD rat model

Fibrosis progression occurred only in rats after moderate gastric bypass, maintained on the FFC diet, despite weight loss and histological improvement in steatosis and inflammation. Further research is needed to better understand the mechanisms underlying the progression of liver fibrosis after MBS. This model is suitable for such an investigation.

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Publication Details

Journal
Clinical Nutrition
Published
2025-07-26
DOI
https://doi.org/10.1016/j.clnu.2025.07.019
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Progression of liver fibrosis after metabolic bariatric surgery in a MASLD rat model

Francesca Sarocchi, Gerhard Prager, Felix B. Langer, Daniel Moritz Felsenreich et al.
Clinical Nutrition
Liver Disease Diagnosis and Treatment
article

Progression of liver fibrosis after metabolic bariatric surgery in a MASLD rat model

Francesca Sarocchi, Gerhard Prager, Felix B. Langer, Daniel Moritz Felsenreich, K. Lackner, Jakob Eichelter, Paula Richwien, Julia Jedamzik, Katharina Wöran, Isabel Büchi, Magdalena Mairinger, Katharina Staufer, Christine Mölzer
article en

Abstract

Fibrosis progression occurred only in rats after moderate gastric bypass, maintained on the FFC diet, despite weight loss and histological improvement in steatosis and inflammation. Further research is needed to better understand the mechanisms underlying the progression of liver fibrosis after MBS. This model is suitable for such an investigation.

Clinical NutritionVol. 52
Medical University of Graz (AT), University Hospital of Bern (CH), Medical University of Vienna (AT)
Austrian Science Fund
Good health and well-being
Openalex Percentile: Top 74%
Liver Disease Diagnosis and Treatment
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Progression of liver fibrosis after metabolic bariatric surgery in a MASLD rat model — Francesca Sarocchi, Gerhard Prager, et al. · Clinical Nutrition (2025) | TGRS Research Map | TGRS