Differential survival outcomes in upper versus lower extremity metastatic bone disease: a retrospective comparative cohort analysis
Lower MBDex is associated with poorer survival outcomes. Operative management is associated with survival benefit in lower MBDex, a benefit not as pronounced in upper MBDex. These findings highlight the importance of differentiating between upper and lower extremity metastases in survival analyses and prediction.
Authors
- Tzu-Hao Tseng (ORCID: https://orcid.org/0000-0002-8564-3149)
- J.-H. Chen
- Jaw‐Lin Wang (ORCID: https://orcid.org/0000-0002-5734-9276)
- Olivier Q. Groot (ORCID: https://orcid.org/0000-0002-5091-3110)
- Chih‐Wei Chen (ORCID: https://orcid.org/0000-0002-9309-5824)
- Chih-Chi Su (ORCID: https://orcid.org/0000-0002-0449-7400)
Institutions
- National Taiwan University (TW)
- University Medical Center Utrecht (NL)
- Massachusetts General Hospital (US)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s13018-025-06079-2
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Taiwan University Hospital
- National Taiwan University