C‐Reactive Protein to Lymphocyte Ratio (CLR) and Lactate Dehydrogenase to Albumin Ratio (LAR) as Prognostic Biomarkers in Acral Melanoma: Association With Tertiary Lymphoid Structures and Immune Cell Infiltration
Elevated CLR and LAR levels are associated with poorer prognosis in AM patients, and this relationship is closely linked to the maturity of TLS and the extent of immune cell infiltration within the TME.
Authors
- Xinyu Su (ORCID: https://orcid.org/0000-0003-1890-8810)
- Zhengyun Zou (ORCID: https://orcid.org/0000-0002-8719-6135)
- Rong Huang (ORCID: https://orcid.org/0000-0001-9541-9020)
- Jiayu Wang (ORCID: https://orcid.org/0000-0003-0558-8643)
- Lianjun Zhao
- Donglin Kang (ORCID: https://orcid.org/0009-0001-9243-8936)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1002/cam4.71078
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China