Phytochemical standardization of Cassia fistula (Pods) and evaluation of diuretic activity
This study aimed to evaluate the diuretic activity of Cassia fistula & the present study was carried out to investigate the diuretic activity of ethanol and aqueous extract of the pods of cassia fistula (CFEE), (CFAE) to make a herbal formulation & were administered to experiment wistar rats orally at the dose level of 100 mg/kg and compared with standard drug furosemide (20 mg/kg). The Lipschistz method used in rats for the experiment purpose. The Cassia fistula formulation showed a market level of increase in urine volume and electrolytes like Na+, K+, and Cl- ion concentration. The moderate diuretic effects was observed and significant diuretic effects from Cassia fistula formulation. Cassia fistula formulation (100 mg/kg) showed more diuretic effect than standard. This might be the first formal report on diuretic activity of cassia fistula plant.
Authors
- Surabhi Yadav
- Ragini Singh
- Ashish Mishra (ORCID: https://orcid.org/0000-0003-1729-0772)
- S. K. Mishra (ORCID: https://orcid.org/0000-0001-8522-0106)
- Shivraj Singh Bhadauriya
Institutions
- United Church of Christ (US)
- Chandra Shekhar Azad University of Agriculture and Technology (IN)
Publication Details
- Journal
- International Journal of Pharmacy and Pharmaceutical Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.33545/26647222.2025.v7.i2a.196
- Primary Topic
- Phytochemistry and biological activity of medicinal plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00