Quantification of hepatic steatosis on post-contrast computed tomography scans using artificial intelligence tools
Automated volumetric mean attenuation of liver and spleen can be used instead of manually placed ROIs for liver fat assessments. Liver attenuation alone in post-contrast phases can be used to assess the presence of moderate-to-severe hepatic steatosis. Correction equations for liver attenuation on post-contrast phase CT scans enable reasonable quantification of liver steatosis, providing potential opportunities for utilizing clinical scans to develop large scale screening or studies in SLD.
Authors
- J. A. Sullivan (ORCID: https://orcid.org/0000-0003-3051-9834)
- Grace L. Su (ORCID: https://orcid.org/0000-0002-8701-774X)
- Stewart C. Wang (ORCID: https://orcid.org/0000-0001-7780-7687)
- Vincent Chen (ORCID: https://orcid.org/0000-0002-0157-6066)
- Brian A. Derstine (ORCID: https://orcid.org/0000-0002-2869-9584)
- Sven A. Holcombe (ORCID: https://orcid.org/0000-0003-0795-7019)
- Manjunath P. Pai (ORCID: https://orcid.org/0000-0001-7119-5034)
Institutions
- VA Ann Arbor Healthcare System (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Abdominal Radiology
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1007/s00261-025-05137-x
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Cancer Institute