Single-slide detection and typing of AL renal amyloidosis: combining mass spectrometry imaging and digital pathology

This study confirmed the capability of MALDI-MSI to detect and type AL amyloidosis, assessing the possibility to integrate an additional computational method for amyloid detection on a single tissue slide.

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Publication Details

Journal
Amyloid
Published
2025-07-26
DOI
https://doi.org/10.1080/13506129.2025.2530532
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Single-slide detection and typing of AL renal amyloidosis: combining mass spectrometry imaging and digital pathology

Vincenzo L’Imperio, Stefania Galimberti, Giulia Capitoli, Federica Mescia et al.
Amyloid
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Single-slide detection and typing of AL renal amyloidosis: combining mass spectrometry imaging and digital pathology

Vincenzo L’Imperio, Stefania Galimberti, Giulia Capitoli, Federica Mescia, Fulvio Magni, Giorgio Cazzaniga, Fabio Pagni, Federico Alberici, Simona Fisogni, Angelo Maggioni, Greta Bindi, Andrew R. Smith, Mauro Mannino
article en

Abstract

This study confirmed the capability of MALDI-MSI to detect and type AL amyloidosis, assessing the possibility to integrate an additional computational method for amyloid detection on a single tissue slide.

AmyloidVol. 32(4)
Brescia University (US), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Azienda Ospedaliera San Gerardo (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), University of Milano-Bicocca (IT), University of Brescia (IT)
Ministero della Salute, Regione Lombardia
Openalex Percentile: Top 84%
Amyloidosis: Diagnosis, Treatment, Outcomes
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Single-slide detection and typing of AL renal amyloidosis: combining mass spectrometry imaging and digital pathology — Vincenzo L’Imperio, Stefania Galimberti, et al. · Amyloid (2025) | TGRS Research Map | TGRS