Clinicopathological Features of HER2 Expressing Lobular Carcinoma of Breast

HER2 overexpression in ILC is frequently associated with pleomorphic features. p-ILC, regardless of HER2 status, portends a worse prognosis. Identifying these features in HER2-positive ILC and classifying them as pleomorphic lobular carcinoma, a more aggressive ILC variant, is crucial for closer patient follow-up.

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Publication Details

Journal
World Journal of Oncology
Published
2025-07-26
DOI
https://doi.org/10.14740/wjon2588
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinicopathological Features of HER2 Expressing Lobular Carcinoma of Breast

Maher A. Sughayer, Khaled Halahleh, Bayan Maraqa, Majd Khader et al.
World Journal of Oncology
HER2/EGFR in Cancer Research
article

Clinicopathological Features of HER2 Expressing Lobular Carcinoma of Breast

Maher A. Sughayer, Khaled Halahleh, Bayan Maraqa, Majd Khader, Hikmat Abdel-Razeq
article en

Abstract

HER2 overexpression in ILC is frequently associated with pleomorphic features. p-ILC, regardless of HER2 status, portends a worse prognosis. Identifying these features in HER2-positive ILC and classifying them as pleomorphic lobular carcinoma, a more aggressive ILC variant, is crucial for closer patient follow-up.

World Journal of OncologyVol. 16(4)
King Hussein Cancer Center (JO)
Gender equality
Openalex Percentile: Top 73%
HER2/EGFR in Cancer Research
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