Ovarian aging, cardiovascular risk and inflammation: insights from the OVA study
These findings do not support the hypothesis that inflammation is a central mechanism linking ovarian aging to cardiovascular risk. The absence of consistent associations across analyses suggests that alternative pathways may underlie this relationship. Further research incorporating a broader range of biomarkers is warranted to elucidate the complex interactions between reproductive aging and cardiovascular health in women.
Authors
- Maria E. Bleil (ORCID: https://orcid.org/0000-0002-2006-4533)
- Charles E. McCulloch (ORCID: https://orcid.org/0000-0002-1279-6179)
- Karla J. Lindquist (ORCID: https://orcid.org/0000-0002-1971-2273)
- Catherine Verhaeghe
- Rita Redberg
- Marc Rosen (ORCID: https://orcid.org/0000-0003-4476-0426)
- Marcelle Ivonne Cedars (ORCID: https://orcid.org/0000-0003-3682-6907)
- Daniel J. Haisenleder
Institutions
- Philips (Finland) (FI)
- University of California, San Francisco (US)
- University of Washington (US)
- University of California System (US)
- University of Virginia (US)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s13048-025-01754-8
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health