Association between taurine transporter SLC6A6 and breast cancer development and prognosis: a Mendelian randomization analysis
Taurine metabolic reprogramming can serve as a potential marker for early breast cancer diagnosis. SLC6A6 participates in breast cancer progression by regulating taurine levels and influencing immune infiltration, representing an independent predictor of breast cancer prognosis and a potential therapeutic target.
Authors
- Xinping Huang (ORCID: https://orcid.org/0000-0002-3110-2128)
- Hui‐Kuo G. Shu (ORCID: https://orcid.org/0000-0002-4060-0874)
- Weixiao Ke (ORCID: https://orcid.org/0000-0002-3159-672X)
- Yifan Zhu
- Wanting Chen (ORCID: https://orcid.org/0009-0001-8487-4068)
- Hai Wang (ORCID: https://orcid.org/0009-0005-2229-8148)
- Man Xu (ORCID: https://orcid.org/0000-0001-6351-7515)
- Wenbin Huang (ORCID: https://orcid.org/0000-0001-6129-9374)
- Yongxia Yang (ORCID: https://orcid.org/0000-0002-0651-8674)
Institutions
- Sun Yat-sen University (CN)
- Guangdong Pharmaceutical University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Department of Health of Guangdong Province (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1007/s12672-025-03246-z
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province