The role and regulatory mechanism of miR-122-5p in the process of pilon fracture healing

Diminished miR-122-5p emerge as a potential prognostic indicator for nonunion in Pilon fractures. miR-122-5p accelerates the healing of Pilon fractures by targeting and inhibiting PDCD4.

Authors

Min Zhou (ORCID: https://orcid.org/0000-0002-4679-0488)
Yang Zhang (ORCID: https://orcid.org/0009-0001-9627-3497)
Lichang Yang
Yingnan Li (ORCID: https://orcid.org/0000-0002-5250-832X)

Institutions

Kunming University of Science and Technology (CN)
Nanjing University of Chinese Medicine (CN)
Wuxi Taihu Hospital (CN)

Publication Details

Journal: Journal of Orthopaedic Surgery and Research
Published: 2025-07-26
DOI: https://doi.org/10.1186/s13018-025-06120-4
Citations: 2
Primary Topic: Bone fractures and treatments
Type: article
Field-Weighted Citation Impact: 2.71

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article

The role and regulatory mechanism of miR-122-5p in the process of pilon fracture healing

Min Zhou, Yang Zhang, Lichang Yang, Yingnan Li

Jul 26, 2025

2 citations

Journal of Orthopaedic Surgery and Research

Bone fractures and treatments

2.71

article

The role and regulatory mechanism of miR-122-5p in the process of pilon fracture healing

Min Zhou, Yang Zhang, Lichang Yang, Yingnan Li

July 26, 2025article en

2 citations

Abstract

Diminished miR-122-5p emerge as a potential prognostic indicator for nonunion in Pilon fractures. miR-122-5p accelerates the healing of Pilon fractures by targeting and inhibiting PDCD4.

Journal of Orthopaedic Surgery and ResearchVol. 20(1)

Kunming University of Science and Technology (CN), Nanjing University of Chinese Medicine (CN), Wuxi Taihu Hospital (CN)

Zero hunger

Openalex Percentile: Top 9%

Bone fractures and treatments

2.71

DOI Open Access PDF OpenAlex

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The role and regulatory mechanism of miR-122-5p in the process of pilon fracture healing — Min Zhou, Yang Zhang, et al. · Journal of Orthopaedic Surgery and Research (2025) | TGRS Research Map | TGRS