Distinct early development trajectories in Nf1± and Tsc2± mouse models of autism
This study provides a nuanced understanding of how these two ASD models differ in their developmental trajectories. It underscores the importance of studying sex differences and early-life developmental markers, as these could offer crucial insights into ASD's progression and neurobiology. The distinct profiles of these models may help guide more targeted therapeutic strategies in the future.
Authors
- João Martins (ORCID: https://orcid.org/0000-0003-2123-8977)
- Helena Ferreira (ORCID: https://orcid.org/0000-0003-4843-9728)
- Joana Gonçalves (ORCID: https://orcid.org/0000-0002-5854-8664)
- Miguel Castelo‐Branco (ORCID: https://orcid.org/0000-0003-4364-6373)
- Sofia Santos (ORCID: https://orcid.org/0000-0003-1331-0625)
Institutions
- University of Coimbra (PT)
Publication Details
- Journal
- Journal of Neurodevelopmental Disorders
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s11689-025-09624-6
- Citations
- 2
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Fundação Luso-Americana para o Desenvolvimento
- Horizon 2020 Framework Programme
- Fundação para a Ciência e a Tecnologia