<scp> LncRNA <i>FENDRR</i> </scp> Inhibits Mitochondrial Apoptosis via <scp>TET2</scp> ‐Mediated <scp>DNA</scp> Demethylation of <scp> <i>MFN1</i> </scp> in <scp>NSCPO</scp>
FENDRR enhances MFN1 expression, maintains mitochondrial fusion, and suppresses apoptosis in HEPM cells. This study provides novel insights into the regulatory role of lncRNAs in NSCPO pathogenesis and identifies FENDRR as a potential therapeutic target.
Authors
- Panpan Zhao (ORCID: https://orcid.org/0000-0001-7579-0033)
- Yu Xia (ORCID: https://orcid.org/0000-0002-5313-100X)
- Haojie Liu (ORCID: https://orcid.org/0000-0002-2595-6012)
- Zhi‐Xin Shan (ORCID: https://orcid.org/0000-0001-6086-5565)
- Zhong‐Yin Zhang (ORCID: https://orcid.org/0000-0001-5527-7910)
- Junqing Ma (ORCID: https://orcid.org/0000-0001-7703-5373)
- Caihong Wu
- Gu Yueguang
Institutions
- The First People’s Hospital of Lianyungang (CN)
- Suzhou Vocational Health College (CN)
- Hangzhou Medical College (CN)
- Hangzhou Cancer Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Oral Diseases
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1111/odi.70035
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China