Late urinary toxicity following radiation in prostate cancer: literature review

Introduction. Radiation damage to the bladder is one of the most common complications of radiation therapy for pelvic malignancies. Materials and methods. The search, analysis and systematization of relevant publications in databases were carried out. e.Library.ru, cyberleninka.ru, PubMed. 64 articles were selected, which are included in this review. Results and discussion. Data on epidemiology, risk factors, pathogenesis, prevention, diagnosis, and treatment of radiation damage to the bladder are presented. Conclusions. Hyperbaric oxygenation, intravesical instillation of glycosaminoglycan acid and chondroitin sulfate, as well as transurethral fulguration remain the most effective methods of treating radiation damage to the bladder.