Effects of glucose and fructose supplementation on serum sex hormone-binding globulin and testosterone levels: Post-hoc analysis of a double-blind randomized controlled trial
Fructose and glucose supplementation do not differentially impact serum SHBG or (free) testosterone levels at a clinically meaningful level. The study was registered at ClinicalTrials.gov (NCT03067428) and were approved by the Medical Ethics Committee of Maastricht University Medical Center (NL58360.068.16).
Authors
- Nynke Simons (ORCID: https://orcid.org/0000-0001-6259-8958)
- Casper G. Schalkwijk (ORCID: https://orcid.org/0000-0003-0190-2690)
- Martijn C.G.J. Brouwers (ORCID: https://orcid.org/0000-0002-8229-3331)
- Edith J. M. Feskens (ORCID: https://orcid.org/0000-0001-5819-2488)
- Emily M. Ploeg (ORCID: https://orcid.org/0000-0002-0735-2020)
- Pomme I. H. G. Simons (ORCID: https://orcid.org/0000-0003-4929-8330)
- Huadong Chen (ORCID: https://orcid.org/0000-0002-9520-6436)
- J. Bons
- Marjo P. H. van de Waarenburg
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Wageningen University & Research (NL)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1016/j.clnesp.2025.07.1123
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nutricia Research Foundation
- Hartstichting
- China Scholarship Council
- Netherlands Heart Institute