Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy

This descriptive case series demonstrates that the current generation of weight loss medications produce a degree of weight loss comparable to bariatric surgery; this is particularly relevant to individuals with obesity who are pursuing organ transplant. Conclusions are limited due to the small, retrospective, and observational nature of this study; however, the results support the hypothesis that medications could revolutionize the organ transplant process by providing a reasonable non-surgical weight loss option for individuals with obesity. Further study with a larger, prospective randomized trial is needed to fully evaluate the viability of utilizing anti-obesity medications for this unique clinical indication.

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Publication Details

Journal
Obesity Pillars
Published
2025-07-26
DOI
https://doi.org/10.1016/j.obpill.2025.100199
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy

Jesse Richards, Mark J. Greenwald, Madisen Fae Dorand, Kevin L Roddy et al.
Obesity Pillars
Diet and metabolism studies
article

Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy

Jesse Richards, Mark J. Greenwald, Madisen Fae Dorand, Kevin L Roddy, Nicholas Hollman
article en

Abstract

This descriptive case series demonstrates that the current generation of weight loss medications produce a degree of weight loss comparable to bariatric surgery; this is particularly relevant to individuals with obesity who are pursuing organ transplant. Conclusions are limited due to the small, retrospective, and observational nature of this study; however, the results support the hypothesis that medications could revolutionize the organ transplant process by providing a reasonable non-surgical weight loss option for individuals with obesity. Further study with a larger, prospective randomized trial is needed to fully evaluate the viability of utilizing anti-obesity medications for this unique clinical indication.

Obesity PillarsVol. 16
University of Oklahoma (US)
Zero hunger
Openalex Percentile: Top 76%
Diet and metabolism studies
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Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy — Jesse Richards, Mark J. Greenwald, et al. · Obesity Pillars (2025) | TGRS Research Map | TGRS