Features of the Balance of Counter-Insular Hormones in the Peripheral Blood of Practically Healthy Inhabitants of High Latitudes

Adrenaline is the main counter-insulin hormone, causing spasms of the vessels of the abdominal organs, skin and mucous membranes, and vessels of the skeletal muscles. The relationship between elevated concentrations of adrenaline and other counter-insulin hormones in the blood serum of high-latitude residents was studied. It was found that elevated concentrations of adrenaline in the blood serum are associated with elevated insulin levels and are recorded equally often in hyperglycemia and hypoglycemia, which reflects the inefficiency of homeostatic mechanisms regulating energy homeostasis under hypoxic conditions. The presence of a simultaneous increase in adrenaline, cortisol, and STH in the blood creates a risk of increasing the sensitivity threshold of hypothalamic inhibition reactions.

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Publication Details

Journal
Biology Bulletin
Published
2025-07-26
DOI
https://doi.org/10.1134/s1062359024614472
Primary Topic
Adrenal Hormones and Disorders
Type
article
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article

Features of the Balance of Counter-Insular Hormones in the Peripheral Blood of Practically Healthy Inhabitants of High Latitudes

L. V. Gubkina, А. В. Самодова, L. K. Dobrodeeva, K. V. Vereshchagina
Biology Bulletin
Adrenal Hormones and Disorders
article

Features of the Balance of Counter-Insular Hormones in the Peripheral Blood of Practically Healthy Inhabitants of High Latitudes

L. V. Gubkina, А. В. Самодова, L. K. Dobrodeeva, K. V. Vereshchagina
article en

Abstract

Adrenaline is the main counter-insulin hormone, causing spasms of the vessels of the abdominal organs, skin and mucous membranes, and vessels of the skeletal muscles. The relationship between elevated concentrations of adrenaline and other counter-insulin hormones in the blood serum of high-latitude residents was studied. It was found that elevated concentrations of adrenaline in the blood serum are associated with elevated insulin levels and are recorded equally often in hyperglycemia and hypoglycemia, which reflects the inefficiency of homeostatic mechanisms regulating energy homeostasis under hypoxic conditions. The presence of a simultaneous increase in adrenaline, cortisol, and STH in the blood creates a risk of increasing the sensitivity threshold of hypothalamic inhibition reactions.

Biology BulletinVol. 52(4)
Northern (Arctic) Federal University (RU), Ural Branch of the Russian Academy of Sciences (RU)
Openalex Percentile: Top 74%
Adrenal Hormones and Disorders
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Features of the Balance of Counter-Insular Hormones in the Peripheral Blood of Practically Healthy Inhabitants of High Latitudes — L. V. Gubkina, А. В. Самодова, et al. · Biology Bulletin (2025) | TGRS Research Map | TGRS