Magnoflorine alleviates colitis-induced anxiety-like behaviors by regulating gut microbiota and microglia-mediated neuroinflammation
Our study revealed that magnoflorine alleviated colitis-induced anxiety-like behaviors by regulating the gut microbiota and microglia-mediated neuroinflammation, which has the potential to treat patients with IBD and anxiety disorders. Video Abstract.
Authors
- Hailong Cao (ORCID: https://orcid.org/0000-0002-0147-7826)
- Siqi Qin (ORCID: https://orcid.org/0009-0001-7039-6966)
- Bingqing Li
- Bangmao Wang (ORCID: https://orcid.org/0000-0003-2796-1584)
- Lei Wang (ORCID: https://orcid.org/0000-0003-1667-2306)
- Mengfan Li (ORCID: https://orcid.org/0000-0002-5558-6366)
- Liying Li (ORCID: https://orcid.org/0000-0003-0470-2328)
- Yue Dong (ORCID: https://orcid.org/0000-0002-9986-409X)
- Jingyi Wang (ORCID: https://orcid.org/0000-0002-4432-5443)
Institutions
- Tianjin Medical University General Hospital (CN)
- Tianjin Infectious Diseases Hospital (CN)
- Affiliated Hospital of Chengde Medical College (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-07-26
- DOI
- https://doi.org/10.1186/s40168-025-02158-y
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China